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Effect of propionyl-L-carnitine on a background of monitored exercise in patients with claudication secondary to peripheral artery disease

68 Despite their popularity and growing market value, the majority of supplements lack evidence-based data regarding safety and efficacy

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, PTS sugars also inhibit the carnitine metabolism expression, but the biotransformation occurs readily under aerobic conditions [23]

Certain medical disorders, however, may prevent carnitine biosynthesis or inhibit its distribution to tissue cells, such as intermittent claudication, heart disease, and certain genetic disorders